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What is Tesamorelin?

Tesamorelin (Trans-3-hexenoic acid GHRH(1-44) analog) is a 44-amino acid full-length GHRH analog + fatty acid conjugate. Full-length GHRH(1-44) analog conjugated to trans-3-hexenoic acid, extending half-life while maintaining full GHRH-R agonism. FDA approved for HIV-associated lipodystrophy (abdominal fat reduction). Produces greater GH pulse amplitude than truncated GHRH analogs (sermorelin, CJC-1295) with full receptor occupancy.

Research Applications

Full-Length GHRH-R Agonism

44aa vs truncated 29aa analogs — receptor activation comparison

FDA-Approved Reference

HIV lipodystrophy indication — abdominal fat and metabolic outcomes

GH Pulse Amplitude

Greater GH release vs sermorelin/CJC-1295 in equivalent dose studies

Visceral Adiposity

Abdominal fat reduction models, lipodystrophy research

Metabolic Effects

GH-mediated lipid metabolism, IGF-1 restoration, body composition

 

Quick Specs

Form C₂₂₁H₃₆₆N₇₂O₆₇S
Purity ≥99% by HPLC — every batch
CAS Number 218949-48-5
Molecular Weight MS molecular weight confirmed — every batch
Specification ≥99% by HPLC — every batch
Shelf Life 24 months unopened
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Manufacture In-house Fmoc SPPS — Qingdao, China
Brand Asia

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
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