What is PT-141?
PT-141 (Bremelanotide — MC4R-preferring melanocortin agonist) is a 7-amino acid cyclic peptide (Melanotan II metabolite). Melanotan II metabolite with preferential MC4R activity over MC1R. Lacks the cyclic structure producing significant tanning (MC1R) activation, making it more selective for CNS MC4R pathways involved in sexual function and appetite. Acts centrally rather than via vascular mechanisms.
Research Applications
MC4R Selective Pharmacology
Preferential MC4R vs MT-II (MC1R+MC4R) — receptor selectivity research
Sexual Function Biology
Hypothalamic MC4R-mediated arousal pathways
Appetite via MC4R
Central appetite modulation, energy balance studies
CNS Melanocortin
Central vs peripheral melanocortin receptor biology
vs Melanotan II
Receptor selectivity comparison — identical structure, different profile
Quick Specs
| Form |
C₅₀H₆₆N₁₂O₁₀ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
189691-06-3 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized PT-141 (Bremelanotide) vial. Swirl gently until dissolved to a clear, colourless solution. PT-141 dissolves readily as a cyclic heptapeptide analogue.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted: 2–8°C for up to 28 days. Protect from light. PT-141 is a cyclic lactam-bridged peptide with good structural stability.
What purity is this QSC compound and how is it verified?
QSC PT-141 (Bremelanotide) is ≥99% HPLC pure with MS-confirmed cyclic heptapeptide identity on every batch. COA is published on the product page and verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
