What is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide — essential cellular coenzyme) is a Dinucleotide coenzyme (C₂₁H₂₇N₇O₁₄P₂). Essential redox coenzyme in oxidative phosphorylation (NADH/NAD+ cycling in ETC), substrate for all 7 sirtuins (SIRT1-7 deacylases), substrate for PARPs (DNA strand break repair), and CD38/cyclic ADP-ribose signalling. Declines 40–60% in most tissues with ageing.
Research Applications
Sirtuin Activation
SIRT1-7 NAD+-dependent deacylase activity, PGC-1α, FOXO3a
Mitochondrial Function
ETC complex I substrate cycling, ATP synthesis efficiency
DNA Repair
PARP1/2 activation — single-strand break repair and genome stability
NAD+ Decline Biology
Age-related NAD+ loss mechanisms — CD38, PARPs, sirtuins
vs NMN/NR
Direct NAD+ vs precursor supplementation — bioavailability comparison
Quick Specs
| Form |
C₂₁H₂₇N₇O₁₄P₂ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
53-84-9 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
12–24 months sealed |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water or sterile saline to the lyophilized NAD+ vial. NAD+ dissolves readily — the solution will appear slightly yellow-orange, which is normal for the nicotinamide adenine dinucleotide chromophore. Do not shake vigorously.
How should this peptide be stored?
Store lyophilized at −20°C, protected from light. NAD+ is sensitive to light and heat — the ribose ring can hydrolyse under acidic or high-temperature conditions. Reconstituted: use within 7–14 days refrigerated, ideally fresh-prepared.
What purity is this QSC compound and how is it verified?
QSC NAD+ is ≥99% pure by HPLC on every batch, with identity confirmed by mass spectrometry. COA is published on the product page and verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
