What is Mazdutide?
Mazdutide (IBI362 — Dual GLP-1R/GCGR agonist (approved China 2024)) is a Weekly injectable fatty acid-conjugated peptide. Weekly injectable dual GLP-1R/GCGR agonist approved in China (2024) — same receptor pairing as survodutide, distinct molecule. GLORY Phase 3: ~10–14% weight reduction, HbA1c reduction in T2D. First dual GLP-1R/GCGR agonist with national approval.
Research Applications
Approved Reference Compound
China-approved dual GLP-1R/GCGR — Phase 3 efficacy data reference
vs Survodutide
Same receptor pair, different pharmacology — comparative research
T2D + Obesity Models
GLORY Phase 3 data: HbA1c and weight reduction combined endpoints
GCGR Thermogenesis
Glucagon-mediated fat oxidation alongside GLP-1R appetite suppression
Weekly Dosing PK
Long-acting fatty acid-conjugated peptide pharmacokinetics
Quick Specs
| Form |
C₂₁₀H₃₂₂N₄₆O₆₇ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
2259884‑03‑0 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
