What is IGF-1 LR3?
IGF-1 LR3 (Long-Arg3 Insulin-Like Growth Factor-1) is a 83-amino acid IGF-1 analog (13-residue N-terminal extension). Long-acting IGF-1 analog with N-terminal 13-residue extension that reduces IGFBP binding by ~1000-fold, extending half-life to 20–30 hours vs 15 minutes for native IGF-1. Activates IGF-1R directly without requiring upstream GHR or hepatic IGF-1 production — IGFBP-resistant in serum-containing media.
Research Applications
IGF-1R Pharmacology
Direct IGF-1 receptor activation, PI3K-Akt-mTOR signalling
Extended Duration Studies
20–30hr half-life vs native IGF-1 (15min) — chronic exposure models
Serum Culture Research
IGFBP-resistant — suitable for serum-containing cell culture media
Muscle Anabolism
Protein synthesis, satellite cell activation, hypertrophy models
vs Native IGF-1
Isolate IGFBP-independent effects by comparison with native IGF-1
Quick Specs
| Form |
C₁₀₄H₁₇₄N₃₂O₃₀S |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
946870-92-4 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
