What is Cagrilintide?
Cagrilintide (Long-acting amylin receptor agonist (CALCR/RAMP)) is a Amylin analog (fatty acid-conjugated for weekly dosing). Long-acting amylin analog activating the amylin receptor complex (calcitonin receptor CALCR + receptor activity-modifying proteins RAMP1/2/3) via brainstem area postrema and hypothalamic circuits — appetite suppression pathway distinct from GLP-1R. Weekly dosing; combined with semaglutide in CagriSema Phase 3.
Research Applications
CALCR/RAMP Pharmacology
Amylin receptor complex activation — area postrema and hypothalamus
Brainstem Appetite Circuit
Independent of GLP-1R — distinct neuronal appetite suppression
Long-Acting Amylin PK
Weekly fatty acid-conjugated amylin analog pharmacokinetics
CagriSema Reference
Phase 3 component — isolated activity vs combination
vs Pramlintide
Short-acting (pramlintide) vs long-acting (cagrilintide) amylin research
Quick Specs
| Form |
Sequence-specific long-acting amylin analog |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
Not publicly standardized (peptide analog) |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial slowly, directing liquid down the wall. Swirl gently — do not shake. Cagrilintide is a fatty acid-modified amylin analogue and may take slightly longer to dissolve than short unmodified peptides.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted: 2–8°C for up to 28 days. Avoid freeze-thaw cycling of reconstituted solution. Store away from direct light.
What purity is this QSC compound and how is it verified?
QSC Cagrilintide is ≥99% pure by HPLC with MS-confirmed molecular identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
