What is AOD-9604?
AOD-9604 (Modified HGH Fragment 177-191 (Tyr-hGH₁₇₇₋₁₉₁)) is a 17-amino acid modified GH C-terminal fragment. Modified HGH C-terminal fragment (Tyr + residues 177-191) activating lipolysis via beta-3 adrenergic receptor pathway in adipose tissue — without GH receptor binding. No IGF-1 stimulation, no anti-insulin effects, no systemic GH anabolic activity. Adipose-selective fat metabolism. Phase 2b human trial data available (obesity).
Research Applications
Adipose-Selective Lipolysis
Beta-3 adrenergic receptor activation — fat breakdown without GHR
No IGF-1 Stimulation
Clean fat metabolism model — no IGF-1, no GHR anabolic confounds
vs HGH Fragment 176-191
Tyr modification: stability, bioavailability and potency differences
Body Composition
Adipose tissue reduction research without systemic GH effects
Beta-3 AR Biology
Receptor activation, cAMP, HSL phosphorylation, fatty acid release
Quick Specs
| Form |
C₇₈H₁₂₃N₂₃O₂₃S₂ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
221231-10-3 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
