What is Semaglutide?
Semaglutide (GLP-1 receptor agonist (94% homology to native GLP-1)) is a 31-amino acid fatty acid-conjugated peptide. Selective GLP-1 receptor agonist with 94% amino acid homology to native GLP-1, fatty acid conjugation enabling weekly dosing. Activates GLP-1R on pancreatic beta cells, hypothalamus, heart, and kidney — glucose-dependent insulin secretion, appetite suppression, gastric emptying delay, and direct cardiovascular effects. SELECT CVOT (2023): 20% MACE reduction.
Research Applications
GLP-1R Pharmacology
Receptor signalling, cAMP cascade, beta cell insulinotropic response
Metabolic Research
Type 2 diabetes, insulin secretion, OGTT models
Obesity & Appetite
Hypothalamic appetite suppression, gastric emptying delay
Cardiovascular
SELECT CVOT reference compound — 20% MACE reduction
NASH/Liver
Hepatic steatosis, NASH resolution, liver fibrosis models
Quick Specs
| Form |
C₁₈₇H₂₉₁N₄₅O₅₉ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
910463-68-2 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized Semaglutide vial by directing the water down the vial wall. Swirl gently until fully dissolved — do not shake. Solution should be clear and colourless. For long-acting GLP-1 research, use a 1mL insulin syringe for precise volume measurement.
How should this peptide be stored?
Lyophilized: −20°C long-term storage. Reconstituted: 2–8°C, use within 21–28 days. Semaglutide is relatively stable due to its C18 fatty acid modification, but avoid repeated freeze-thaw cycles. Discard if solution becomes cloudy.
What purity is this QSC compound and how is it verified?
QSC Semaglutide is tested at ≥99% HPLC purity with mass spectrometry identity confirmation on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
