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What is TB-500?

TB-500 (Thymosin Beta-4 fragment (Ac-LKKTETQ)) is a 7-amino acid synthetic fragment. Sequesters G-actin to promote cell migration, activates an independent VEGF-mediated angiogenesis pathway, and modulates NF-κB to reduce inflammatory signalling. Non-overlapping with BPC-157 — complementary repair targets.

Research Applications

Cell Migration & Wound Repair

Actin sequestration enabling directed fibroblast/endothelial migration

Independent Angiogenesis

VEGF pathway activation distinct from BPC-157 NO/VEGF axis

Anti-Inflammatory

NF-κB modulation and inflammatory cytokine reduction

Cardiac Repair

Cardiomyocyte protection and cardiac tissue healing models

Muscle Repair

Skeletal muscle satellite cell activation and regeneration

 

Quick Specs

Form C₂₁₂H₃₅₀N₅₆O₇₈S
Purity ≥99% by HPLC — every batch
CAS Number Not officially assigned (synthetic peptide fragmen
Molecular Weight MS molecular weight confirmed — every batch
Specification ≥99% by HPLC — every batch
Shelf Life 24 months unopened
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Manufacture In-house Fmoc SPPS — Qingdao, China
Brand China

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized TB-500 vial. Swirl gently until dissolved — TB-500 (Thymosin Beta-4 fragment Ac-SDKP) dissolves readily to a clear solution. For large vials (10mg+), you may need to allow 5 minutes for full dissolution.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted TB-500 is stable at 2–8°C for up to 28 days. Keep away from direct light and avoid repeated freeze-thaw cycles of reconstituted solution.
What purity is this QSC compound and how is it verified?
QSC TB-500 is ≥99% pure by HPLC with MS-confirmed molecular identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
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