What is TB-500?
TB-500 (Thymosin Beta-4 fragment (Ac-LKKTETQ)) is a 7-amino acid synthetic fragment. Sequesters G-actin to promote cell migration, activates an independent VEGF-mediated angiogenesis pathway, and modulates NF-κB to reduce inflammatory signalling. Non-overlapping with BPC-157 — complementary repair targets.
Research Applications
Cell Migration & Wound Repair
Actin sequestration enabling directed fibroblast/endothelial migration
Independent Angiogenesis
VEGF pathway activation distinct from BPC-157 NO/VEGF axis
Anti-Inflammatory
NF-κB modulation and inflammatory cytokine reduction
Cardiac Repair
Cardiomyocyte protection and cardiac tissue healing models
Muscle Repair
Skeletal muscle satellite cell activation and regeneration
Quick Specs
| Form |
C₂₁₂H₃₅₀N₅₆O₇₈S |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
Not officially assigned (synthetic peptide fragmen |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
China |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized TB-500 vial. Swirl gently until dissolved — TB-500 (Thymosin Beta-4 fragment Ac-SDKP) dissolves readily to a clear solution. For large vials (10mg+), you may need to allow 5 minutes for full dissolution.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted TB-500 is stable at 2–8°C for up to 28 days. Keep away from direct light and avoid repeated freeze-thaw cycles of reconstituted solution.
What purity is this QSC compound and how is it verified?
QSC TB-500 is ≥99% pure by HPLC with MS-confirmed molecular identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)