What is Thymosin Alpha-1?
Thymosin Alpha-1 (Tα1 — Thymalfasin (28-aa thymic peptide)) is a 28-amino acid N-terminally acetylated thymic peptide. Naturally occurring thymic peptide activating TLR2 and TLR9 on dendritic cells and T-cells, promoting type I IFN production in plasmacytoid dendritic cells, Th1 polarisation, T-cell maturation in thymus, and NK cell cytotoxicity. Approved in 35+ countries as thymalfasin. N-terminal acetylation required for activity.
Research Applications
TLR2/TLR9 Signalling
Innate immune activation via toll-like receptor pathways
Type I Interferon
IFN-α/β production in plasmacytoid dendritic cells
T-Cell Maturation
Thymic maturation, CD3/CD4/CD8 upregulation on thymocytes
Th1 Polarisation
Cell-mediated immunity vs humoral — IL-12, IFN-γ research
NK Cell Activation
Natural killer cell cytotoxicity — antitumour and antiviral
Quick Specs
| Form |
C₂₁₁H₃₆₆N₇₂O₆₇S (approximate; sequence-dependent) |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
62304-98-7 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial. Thymosin Alpha-1 (28 amino acid peptide) dissolves readily to a clear, colourless solution. Swirl gently and do not shake.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted: 2–8°C for up to 28 days. Thymosin Alpha-1 (Thymalfasin) is generally stable under refrigeration once reconstituted. Avoid freeze-thaw cycling.
What purity is this QSC compound and how is it verified?
QSC Thymosin Alpha-1 is ≥99% HPLC pure with MS-confirmed 28-amino acid sequence on every batch. COA is published on the product page and verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
