What is Semax?
Semax (ACTH(4-10) derivative — cognitive neuropeptide) is a 7-amino acid synthetic ACTH(4-10) derivative. ACTH(4-10) derivative upregulating BDNF and NGF expression in multiple brain regions, modulating monoaminergic systems (dopamine, serotonin, noradrenaline), and producing neuroprotection in cerebral ischemia models. Approved as nasal spray in Russia. Greater potency and duration than parent ACTH(4-10).
Research Applications
BDNF/NGF Upregulation
Brain-derived and nerve growth factor expression research
Monoaminergic Modulation
Dopamine, serotonin, noradrenaline system effects
Neuroprotection
Cerebral ischemia, stroke, and excitotoxicity models
Cognitive Function
Learning, memory, and attention mechanistic research
vs Selank
Semax (activating/BDNF) vs Selank (anxiolytic/GABA) comparison
Quick Specs
| Form |
C₃₇H₅₁N₉O₁₀S |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
80714-61-0 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized Semax vial. Semax is a heptapeptide (ACTH(4-10)-Pro-Gly-Pro) that dissolves readily. Swirl gently to a clear colourless solution. Some researchers dilute further with saline for intranasal administration.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted: 2–8°C for up to 28 days. Semax is relatively stable — the Pro-Gly-Pro C-terminal extension was specifically added to increase proteolytic resistance vs. native ACTH(4-10).
What purity is this QSC compound and how is it verified?
QSC Semax (ACTH(4-10)-Pro-Gly-Pro) is ≥99% HPLC pure with MS-confirmed 7-amino acid sequence on every batch. COA is published on the product page and verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
