What is SS-31?
SS-31 (Elamipretide — Bendavia — MTP-131 (cardiolipin-binding tetrapeptide)) is a 4-amino acid aromatic-cationic tetrapeptide. Aromatic-cationic tetrapeptide concentrating 1000× in the inner mitochondrial membrane by electrostatic and aromatic interactions with cardiolipin. Stabilises cristae architecture, preserves electron transport chain (ETC) complex I–IV organisation, reduces mitochondrial ROS production, and maintains ATP synthesis efficiency under ischemia and oxidative stress.
Research Applications
Cardiolipin Binding
Inner mitochondrial membrane cardiolipin interaction and cristae stabilisation
ETC Complex Preservation
Complex I–IV organisation under ischemia and oxidative stress
Mitochondrial ROS
Superoxide reduction at ETC, mitochondrial antioxidant research
Heart Failure Research
STELA, MEND-HF Phase 2 clinical reference compound
Neurodegeneration
Mitochondrial dysfunction in AD, PD, ALS models
Quick Specs
| Form |
C₃₂H₄₉N₉O₅ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
736992-21-5 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized SS-31 (Elamipretide) vial. SS-31 is a small tetrapeptide (Ar-2’6′-Dmt-Lys-Phe-NH₂) that dissolves immediately to a clear, colourless solution.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted: 2–8°C for up to 28 days. The aromatic residues in SS-31 provide good structural stability; however, avoid oxidizing conditions and prolonged light exposure.
What purity is this QSC compound and how is it verified?
QSC SS-31 (Elamipretide/Bendavia) is ≥99% HPLC pure with MS-confirmed tetrapeptide identity on every batch. COA is published on the product page and verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
