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What is BAM15?

BAM15 is a protonophore that dissipates the mitochondrial proton gradient — uncoupling OXPHOS from ATP synthesis and driving energy dissipation as heat. Critically, BAM15 does not penetrate the plasma membrane and does not cause hyperthermia in vivo — the primary safety limitation of classical uncouplers (DNP). Romero et al. 2020: fat mass reduction and improved insulin sensitivity in DIO mice without hyperthermia. CAS 2061936-25-0.

Research Applications

Mitochondrial Uncoupling

Proton gradient dissipation — heat vs ATP thermogenesis research

Safe Uncoupler Reference

No plasma membrane penetration — avoids DNP hyperthermia

Obesity/Metabolic

Romero 2020: fat mass reduction + insulin sensitivity in DIO mice

UCP1 Comparison

Pharmacological vs physiological (BAT UCP1) uncoupling

Mitochondrial Bioenergetics

OCR/ECAR (Seahorse), proton leak, coupling efficiency

 

Quick Specs

Form C₁₃H₁₈F₆N₂O₃
Purity ≥99% by HPLC — every batch
CAS Number 2061936-25-0
Molecular Weight MS molecular weight confirmed — every batch
Specification ≥99% by HPLC — every batch
Shelf Life 24 months unopened
Storage Room temperature sealed | cool, dry storage
Manufacture In-house synthesis — Qingdao, China
Brand China

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
QSC research tablets are supplied as pre-dosed oral tablets at the stated concentration. No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight. Keep in the original container. Properly stored tablets remain stable for 2–3 years.
What purity is this QSC compound and how is it verified?
QSC research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
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