What is Tamoxifen?
Tamoxifen is a first-generation triphenylethylene SERM — ER antagonist in breast tissue, partial ER agonist in bone/liver/uterus. Metabolised to endoxifen (CYP2D6) — the primary active metabolite. Also the most widely used inducer for tamoxifen-inducible CreERT2/loxP conditional knockout mouse models. CAS 10540-29-1.
Research Applications
Breast Cancer Research
ER antagonist in mammary tissue — foundational hormone-sensitive cancer
SERM Pharmacology
Tissue-selective ERα/ERβ agonism/antagonism — bone, liver, uterus vs breast
Tamoxifen-Inducible Cre
Primary inducing agent for CreERT2/loxP conditional knockout models
CYP2D6 Metabolism
Endoxifen activation — pharmacogenomic metabolism research
HPG Axis
Hypothalamic ER antagonism → LH/FSH restoration in PCT models
Quick Specs
| Form |
C₂₆H₂₉NO |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
10540-29-1 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
QSC research tablets are supplied as pre-dosed oral tablets at the stated concentration. No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight. Keep in the original container. Properly stored tablets remain stable for 2–3 years.
What purity is this QSC compound and how is it verified?
QSC research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
