What is Tadalafil?
Tadalafil (Cialis) is a selective PDE5 inhibitor with the longest half-life in its class (~17.5hr, duration up to 36hr). Prevents cGMP degradation in smooth muscle, sustaining NO-mediated vasodilation. FDA-approved for erectile dysfunction, BPH, and pulmonary arterial hypertension (PAH/Adcirca). CAS 171596-29-5.
Research Applications
NO/cGMP Pathway
PDE5 inhibition → sustained cGMP → smooth muscle relaxation
Pulmonary Hypertension
PAH vasodilation — Adcirca indication — pulmonary vascular resistance
Long-Duration Protocol
17.5hr half-life — chronic dosing and sustained inhibition studies
Cardiac Preload/Afterload
Venodilation and arterial effects — cardiac function modelling
vs PT-141 Pairing
Peripheral PDE5 (tadalafil) + central MC4R (PT-141) — erectile physiology
Quick Specs
| Form |
C₂₂H₁₉N₃O₄ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
171596-29-5 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
QSC research tablets are supplied as pre-dosed oral tablets at the stated concentration. No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight. Keep in the original container. Properly stored tablets remain stable for 2–3 years.
What purity is this QSC compound and how is it verified?
QSC research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
