What is LGD-4033 Ligandrol?
LGD-4033 (Ligandrol) is a non-steroidal SARM — high affinity and selectivity for AR in muscle and bone with reduced activity in androgenic tissues (prostate, skin). Research: tissue-selective AR agonism, muscle wasting/sarcopenia, bone density, comparative anabolic activity vs testosterone. CAS 1165910-22-4.
Research Applications
Tissue-Selective AR Agonism
High muscle/bone AR affinity — reduced prostate/skin androgenicity
Muscle Wasting/Sarcopenia
Lean mass models — cancer cachexia, HIV wasting
Bone Density
AR agonism in bone — osteoporosis and fracture healing models
SARM vs AAS Comparison
Selective vs non-selective AR activation — mechanistic dissection
Anabolic Signalling
AR-dependent gene programme — MPS, IGF-1, myosin heavy chain
Quick Specs
| Form | C₁₄H₁₂F₆N₂O |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 1165910-22-4 |
| Molecular Weight | MS molecular weight confirmed — every batch |
| Specification | ≥99% by HPLC — every batch |
| Shelf Life | 24 months unopened |
| Storage | Room temperature sealed | cool, dry storage |
| Manufacture | In-house synthesis — Qingdao, China |
| Brand | China |
Frequently Asked Questions
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
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