What is IGF-1 LR3 0.1mg?
IGF-1 LR3 (Long R3 IGF-1) is a synthetic analog of Insulin-like Growth Factor 1 with an arginine substitution at position 3 and an N-terminal 13-amino acid extension that dramatically reduces IGF-binding protein (IGFBP) affinity — extending plasma half-life from ~12 minutes (native IGF-1) to ~20-30 hours. Activates IGF-1R (IGF-1 receptor) promoting glucose uptake, protein synthesis, anti-apoptosis, and myogenic differentiation. The 0.1mg/vial format provides a micro-dose format for dose-finding, in vitro cell culture research, and low-dose receptor binding studies.
Research Applications
Myogenesis & Muscle Cell Research
IGF-1R activation drives myogenic differentiation (MyoD, myogenin expression), protein synthesis (mTOR/S6K pathway), and satellite cell activation. 0.1mg format for in vitro C2C12 myoblast research.
IGFBP Interaction Studies
LR3 modification reduces IGFBP-3 affinity — enables comparison of IGFBP-bound vs free IGF-1 bioavailability. Ligand competition assays.
Dose-Finding & Receptor Pharmacology
0.1mg/vial suits low-concentration in vitro dose-response curves and EC50 determination for IGF-1R pharmacology.
Quick Specs
| Form |
Lyophilised powder, 10-vial kit |
| Purity |
≥99% HPLC, MS confirmed |
| Specification |
≥99% HPLC, MS confirmed |
| Storage |
−20°C lyophilised; 4°C reconstituted, 7 days |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
−20°C lyophilised; 4°C reconstituted, 7 days
