What is Epitalon?
Epitalon (Epithalon — AEDG synthetic tetrapeptide (pineal gland)) is a 4-amino acid synthetic tetrapeptide (Ala-Glu-Asp-Gly). Synthetic pineal tetrapeptide activating hTERT (telomerase reverse transcriptase) expression in somatic cells, reducing oxidative stress markers (MDA, SOD, catalase), and restoring melatonin circadian amplitude in aged models. Khavinson longevity studies: 13–25% lifespan extension in rodents and extended human cohort data.
Research Applications
hTERT Telomerase
Somatic cell telomerase activation — replicative senescence delay
Telomere Length
Telomere length maintenance beyond Hayflick limit in cell culture
Pineal & Melatonin
Pinealocyte activation, melatonin circadian rhythm restoration
Oxidative Stress
MDA reduction, SOD/catalase upregulation in aged tissue models
Longevity Research
Khavinson rodent lifespan studies — 13–25% extension reference
Quick Specs
| Form |
C₆₅H₈₄N₁₆O₁₉ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
307297-39-8 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized Epitalon (AEDG tetrapeptide) vial. Epitalon is a very small tetrapeptide and dissolves almost instantly to a clear, colourless solution. Swirl gently.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted: 2–8°C for up to 28 days. As a tetrapeptide, Epitalon is quite stable. Avoid direct light exposure of reconstituted solution.
What purity is this QSC compound and how is it verified?
QSC Epitalon (Ala-Glu-Asp-Gly) is ≥99% pure by HPLC with MS-confirmed tetrapeptide identity on every batch. COA is published on the product page and verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)