What is Vitamin D3 (D320 — 20,000 IU/mL)?
Vitamin D3 (Cholecalciferol 20,000 IU/mL — high-concentration injectable) is cholecalciferol — C₂₇H₄₄O, MW 384.6 — at 20,000 IU/mL in oil-based injectable solution. Cholecalciferol is the natural form of Vitamin D3, converted to 25-hydroxyvitamin D3 (calcidiol) in the liver and then to the active 1,25-dihydroxyvitamin D3 (calcitriol) in the kidney. Calcitriol activates the vitamin D receptor (VDR) — a nuclear receptor regulating calcium/phosphorus metabolism, immune function, cell proliferation, and hundreds of downstream genes.
Research Applications
Vitamin D Receptor (VDR) Research
Calcitriol-VDR nuclear receptor activation — gene expression, calcium metabolism, immune regulation
Calcium & Bone Metabolism
Intestinal calcium absorption, osteoblast/osteoclast regulation, and bone mineralisation
Immune Modulation
VDR in T-cell, macrophage, and dendritic cell function — innate and adaptive immunity
Deficiency Correction Models
Rapid repletion of severe Vitamin D deficiency in research models using high-dose injectable
25(OH)D3 Pharmacokinetics
High-dose D3 conversion to calcidiol — hepatic hydroxylation kinetics and serum 25(OH)D3 elevation
Quick Specs
| Form | C₂₇H₄₄O |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 67-97-0 |
| Molecular Weight | MS confirmed — every batch |
| Specification | ≥99% by HPLC — every batch |
| Shelf Life | 24 months (unopened) |
| Storage | 2–8°C | Protect from light |
| Brand | China |