What is Exemestane?
Exemestane (Aromasin — irreversible steroidal aromatase inhibitor (Type I AI)) is a Small molecule C₂₀H₂₄O₂, MW 296.4. Irreversible steroidal aromatase inhibitor (Type I, mechanism-based) that covalently inactivates CYP19A1 after single binding — unlike reversible non-steroidal AIs. Complete suppression of oestrogen synthesis in all tissues. FDA approved for breast cancer. No rebound aromatisation after discontinuation.
Research Applications
Irreversible CYP19A1 Inactivation
Mechanism-based aromatase inhibition — no enzyme recovery after binding
Type I vs Type II AI
Irreversible (exemestane) vs reversible (anastrozole/letrozole) comparison
Oestrogen Deprivation Research
Complete oestrogen suppression — breast cancer models, bone research
Aromatase Biology
CYP19A1 enzyme kinetics, active site interaction, inactivation mechanism
Breast Cancer Research
FDA-approved compound reference — hormonal breast cancer models
Quick Specs
| Form |
C₂₀H₂₄O₂, MW 296.4. |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
107868-30-4 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
As indicated by manufacturer |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
China |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
QSC research tablets are supplied as pre-dosed oral tablets at the stated concentration. No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight. Keep in the original container. Properly stored tablets remain stable for 2–3 years.
What purity is this QSC compound and how is it verified?
QSC research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
