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What is Tirzepatide?

Tirzepatide (Dual GIP+GLP-1 receptor agonist) is a 39-amino acid dual-modified synthetic peptide. First approved dual GIP and GLP-1 receptor co-agonist — one molecule activating both incretin receptors simultaneously. GIPR co-agonism adds: adipose lipolysis, thermogenesis, and hypothalamic GLP-1R sensitisation. SURMOUNT-5 (2025): 20.2% vs 13.7% mean weight reduction vs semaglutide 2.4mg at 72 weeks. SURPASS-2: superior HbA1c vs semaglutide 1mg.

Research Applications

Dual Incretin Pharmacology

GIP+GLP-1R co-agonism, receptor interaction, GIPR adipose signalling

T2D Research

SURPASS program — up to 2.58% HbA1c reduction vs placebo

Obesity Models

SURMOUNT-1: 22.5% weight reduction (15mg, 72 weeks)

NASH/Liver

SYNERGY-NASH: 62.4% NASH resolution at 10mg

vs Semaglutide

Head-to-head SURMOUNT-5 reference compound

 

Quick Specs

Form C₂₂₅H₃₄₈N₄₈O₆₈
Purity ≥99% by HPLC — every batch
CAS Number 2023788-19-2
Molecular Weight MS molecular weight confirmed — every batch
Specification ≥99% by HPLC — every batch
Shelf Life 24 months unopened
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Manufacture In-house Fmoc SPPS — Qingdao, China
Brand Asia

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL of bacteriostatic water slowly to the lyophilized vial. Gently swirl — do not shake or vortex. The peptide dissolves to a clear, colourless solution. Use a 1mL insulin syringe for precise sub-milligram dosing of this potent dual agonist.
How should this peptide be stored?
Store lyophilized at −20°C. Reconstituted solution: 2–8°C refrigerator, use within 21–28 days. Avoid repeated freeze-thaw cycles and direct light exposure. Reconstituted Tirzepatide is stable for approximately 3–4 weeks refrigerated.
What purity is this QSC compound and how is it verified?
QSC Tirzepatide is ≥99% pure by HPLC peak area analysis and MS-confirmed for molecular weight on every production batch. COA is published on the product page and independently verifiable via verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
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