What is Survodutide?
Survodutide (Dual GLP-1R/GCGR agonist — BI 456906) is a Synthetic fatty acid-conjugated peptide. Dual GLP-1R and glucagon receptor co-agonist (not GIPR). Unlike tirzepatide (GLP-1R+GIPR), survodutide targets GLP-1R+GCGR — the same receptor pairing as the glucagon component of retatrutide. NASH Phase 2b: significant liver fat reduction, NASH resolution. Clinical-stage GCGR+GLP-1R compound.
Research Applications
GLP-1R+GCGR Co-agonism
Distinct from tirzepatide (GLP-1R+GIPR) — GCGR instead of GIPR
GCGR Research
Glucagon receptor activation without GIPR confound
NASH Research
Phase 2b reference compound — liver fat and NASH resolution
Thermogenesis
GCGR-mediated fat oxidation and energy expenditure
Mechanistic Comparison
vs retatrutide (triple) and tirzepatide (different dual)
Quick Specs
| Form |
Large synthetic peptide (sequence-specific; propri |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
Not publicly standardized |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
As indicated by manufacturer |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Asia |
Certificate of Analysis (COA)
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
