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What is AHK-Cu??

AHK-Cu (Alanine-Histidine-Lysine Copper Tripeptide-3, CAS 49557-75-7) is a synthetic copper-binding tripeptide specifically engineered to target hair follicle signalling. Unlike the naturally occurring GHK-Cu (Copper Tripeptide-1), AHK-Cu is lab-designed with superior copper-binding stability and a more follicle-directed mechanism — stimulating dermal papilla cells, promoting VEGF-mediated angiogenesis around the follicle, and extending the anagen (growth) phase. It also retains collagen and elastin synthesis activity relevant to skin remodelling research.

Research Applications

Hair Follicle Biology

Dermal papilla cell stimulation, anagen/telogen ratio modulation, follicular VEGF upregulation

Scalp Angiogenesis

Perifollicular blood vessel formation, nutrient delivery pathway research

Skin Remodelling

Fibroblast collagen and elastin synthesis, ECM metalloproteinase/inhibitor balance

Copper Homeostasis

Cu²⁺ chelation dynamics, lysyl oxidase cofactor activity, redox signalling

Anti-Inflammatory

TNF-α/IL-6 modulation in dermal fibroblast models, wound healing cascade

 

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 49557-75-7
Molecular Weight MS molecular weight confirmed — every batch
Specification ≥99% by HPLC — every batch
Shelf Life 24 months unopened
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Manufacture In-house Fmoc SPPS — Qingdao, China
Brand Asia

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
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