What is EPO (High-Dose)??
This 10,000 IU/vial high-dose formulation of recombinant human erythropoietin (rhEPO) is designed for research protocols requiring elevated EPO concentrations — dose-escalation studies, supraphysiological receptor saturation kinetics, high-burden anaemia models, or multi-arm concentration-response assays. EPO binds the homodimeric EPOR, activating JAK2/STAT5, PI3K/Akt, and MAPK pathways to stimulate red blood cell differentiation, survival, and haemoglobin synthesis. EPOR expression in non-haematopoietic tissues also supports neuroprotection and cardioprotection research.
Research Applications
High-Dose Erythropoiesis
Supraphysiological RBC stimulation, dose-escalation BFU-E/CFU-E models, EPOR saturation kinetics
JAK2/STAT5 Signalling
EPOR kinase cascade profiling at high receptor occupancy
Severe Anaemia Models
High-burden chemotherapy-induced, renal, and haemolytic anaemia preclinical models
Neuroprotection
High-dose EPOR activation in neuronal ischaemia, spinal cord injury, and TBI models
Cardioprotection
Cardiomyocyte EPOR, myocardial infarction protection, high-dose cardiac remodelling studies
Quick Specs
| Form |
Lyophilized powder |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
11096-26-7 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
-20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (2–4 weeks)
