What is N-Acetyl Epitalon Amidate?
N-Acetyl Epitalon Amidate is a stabilised derivative of Epitalon (Ala-Glu-Asp-Gly tetrapeptide) with N-terminal acetylation and C-terminal amidation to resist proteolytic degradation. Studied for telomerase activation, melatonin regulation, and neuroendocrine axis modulation. Research use only.
Research Applications
Telomerase Activation Research
TERT expression, telomere length maintenance, cellular immortalisation models
Neuroendocrine Research
Pineal function, melatonin synthesis, circadian rhythm modulation
Cellular Aging Models
Senescent cell studies, replicative lifespan, p53/p21 pathway
Antioxidant Studies
Lipid peroxidation inhibition, oxidative stress markers, enzymatic antioxidants
Peptide Stability Research
Proteolytic resistance of N-acetyl/C-amide modifications, pharmacokinetics
Quick Specs
| Form |
C₁₄H₂₂N₄O₇ (acetylated + amidated), MW ~374.3 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
307297-39-8 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
-20°C sealed | 2–8°C reconstituted (4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1 mL bacteriostatic water to the lyophilized vial, directing liquid down the inner wall. Swirl gently until clear — dissolves within 1 minute. This modified form is highly soluble.
How should this peptide be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 4 weeks. The acetylated/amidated modifications provide enhanced stability over native Epitalon.
What purity is this QSC compound and how is it verified?
N-terminal acetylation and C-terminal amidation protect both ends of the peptide from exopeptidase cleavage, dramatically extending plasma half-life and improving bioavailability compared to the native Ala-Glu-Asp-Gly tetrapeptide.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (4 weeks)
