What is PTD-DBM?
PTD-DBM is a cell-penetrating peptide construct combining a Protein Transduction Domain (PTD) and a Dvl-binding motif (DBM). It blocks the inhibitory CXXC5–Dishevelled interaction, restoring Wnt/β-catenin signalling. Studied for dermal papilla cell activation, hair follicle neogenesis, and wound healing. Research use only.
Research Applications
Wnt/β-Catenin Pathway Research
β-catenin nuclear translocation, TCF/LEF reporter assays, pathway activation
Hair Follicle Regeneration
Dermal papilla cell proliferation, anagen induction, follicle neogenesis models
Skin Wound Healing
Keratinocyte re-epithelialisation, fibroblast migration, ECM deposition
CXXC5 Biology
Wnt suppressor interaction, negative feedback loop, Dkk1 regulation
Cell-Penetrating Peptide Research
PTD transduction efficiency, intracellular delivery, nuclear targeting
Quick Specs
| Form |
Proprietary peptide construct (PTD + DBM fusion) |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
2411025-13-3 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
-20°C sealed | 2–8°C reconstituted (3 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1 mL bacteriostatic water to the lyophilized vial, directing liquid down the inner wall. Swirl gently until clear. PTD-DBM dissolves readily within 1–2 minutes due to its hydrophilic PTD domain.
How should this peptide be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 3 weeks. Minimize light exposure and freeze-thaw cycles to preserve the PTD structure.
What purity is this QSC compound and how is it verified?
PTD-DBM contains a Dishevelled-binding motif (DBM) that competitively disrupts the inhibitory CXXC5–Dvl interaction. This relieves suppression of the Wnt/β-catenin cascade, promoting target gene transcription. The PTD domain enables intracellular delivery without transfection.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (3 weeks)
