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What is Alprostadil?

Alprostadil is a synthetic form of Prostaglandin E1 (PGE1). Acts on EP receptors (EP2/EP3/EP4) to stimulate adenylyl cyclase, raise intracellular cAMP, and relax vascular smooth muscle. Studied for penile vascular physiology, peripheral artery disease models, and platelet aggregation inhibition. Research use only.

Research Applications

Vascular Smooth Muscle Research

EP receptor signalling, cAMP cascade, vasodilation assays

Erectile & Penile Physiology

Corpus cavernosum smooth muscle relaxation, haemodynamic models

Peripheral Vascular Research

PAD models, ischaemia-reperfusion, microcirculation studies

Platelet Aggregation

PGE1-mediated platelet cAMP elevation, anti-aggregatory signalling

Pulmonary Hypertension Models

Pulmonary vascular resistance, endothelial function, NO interaction

 

Quick Specs

Form C₂₀H₃₄O₅, MW 354.5
Purity ≥99% by HPLC — every batch
CAS Number 745-65-3
Molecular Weight MS molecular weight confirmed — every batch
Specification ≥99% by HPLC — every batch
Shelf Life 24 months (unopened)
Storage 2–8°C sealed | reconstituted use within 48h
Manufacture In-house Fmoc SPPS — Qingdao, China
Brand China

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2 mL bacteriostatic water to the lyophilized vial. Swirl gently until clear — dissolves readily within 1 minute. Use within 24 hours of reconstitution for best stability.
How should this peptide be stored?
Store lyophilized vials at 2–8°C or −20°C for long-term. Reconstituted solution should be used promptly; stability at 2–8°C is limited to 24–48 hours. PGE1 is susceptible to oxidation.
What purity is this QSC compound and how is it verified?
Alprostadil is a well-characterised PGE1 analogue used in vascular biology, erectile physiology, and platelet research. It enables precise EP receptor activation and cAMP pathway manipulation in smooth muscle and endothelial cell models.
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
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