What is Teriparatide?
Teriparatide is the biologically active N-terminal 34-amino acid fragment of human parathyroid hormone (PTH 1-34). Binds PTH1R to activate adenylyl cyclase and PKC pathways, stimulating osteoblastogenesis and bone matrix deposition. Studied as an anabolic bone agent in osteoporosis research. Research use only.
Research Applications
Anabolic Bone Formation
Osteoblast proliferation, bone matrix synthesis, trabecular architecture
PTH1R Signalling
cAMP/PKA and PKC pathways, receptor internalisation, downstream targets
Osteoporosis Models
OVX models, glucocorticoid-induced osteoporosis, fracture healing
Calcium Homeostasis
Renal calcium reabsorption, 1,25(OH)₂D₃ synthesis, serum calcium dynamics
Osteocyte & Osteoclast Research
RANKL/OPG balance, bone remodelling cycle, sclerostin interaction
Quick Specs
| Form |
C₁₈₁H₂₉₁N₅₅O₅₁S₂, MW 4117.8 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
52232-67-4 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
-20°C sealed | 2–8°C reconstituted (4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2 mL bacteriostatic water to the lyophilized vial, directing liquid down the inner wall. Swirl gently until clear. Teriparatide dissolves within 1–2 minutes.
How should this peptide be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 28 days. Avoid agitation and light exposure.
What purity is this QSC compound and how is it verified?
Teriparatide is the 1-34 N-terminal fragment of PTH (84 amino acids). The 1-34 fragment retains full PTH1R binding and biological activity. Importantly, intermittent PTH(1-34) stimulation promotes anabolic bone formation, while continuous exposure favours bone resorption — a key distinction in research design.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (4 weeks)
