What is Isotretinoin (13-cis-Retinoic Acid)?
Isotretinoin (13-cis-retinoic acid) is a synthetic retinoid binding RAR and RXR nuclear receptors. Induces sebocyte apoptosis, reduces sebaceous gland size, normalises keratinocyte differentiation, and has anti-proliferative effects in neuroblastoma. Research tool for retinoid receptor pharmacology, sebaceous biology, and differentiation research. Research use only.
Research Applications
RAR/RXR Pharmacology
Retinoid receptor binding, RARE-mediated transcription, retinoid signalling cascade
Sebaceous Gland Research
Sebocyte apoptosis, sebum suppression, SCD1/FASN pathway modulation
Keratinocyte Differentiation
Follicular hyperkeratinisation inhibition, skin barrier, cornification
Neuroblastoma Differentiation
MYCN suppression, neural differentiation, neurite outgrowth induction
Retinoid Bulk Research
Large-scale receptor binding studies, RARE reporter assays, SAR with isomers
Quick Specs
| Form |
C₂₀H₂₈O₂, MW 300.4 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
4759-48-2 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
QSC raw powder compounds are supplied as bulk crystalline or amorphous powder in a sealed, labelled container at the stated quantity. No reconstitution is required — the powder is ready for weighing and use in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct light. Keep in the original sealed container. Properly stored raw powder remains stable for 2–3 years.
What purity is this QSC compound and how is it verified?
All QSC raw powder compounds are tested to ≥99% purity by HPLC on every production batch, with MS-confirmed identity. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
