What is Anastrozole (Arimidex)?
Anastrozole (Arimidex) is a non-steroidal triazole aromatase inhibitor — reversibly blocks CYP19A1 with high selectivity. Reduces serum estradiol ~80–90% in research models. Widely used AI reference compound for estrogen suppression, aromatase pharmacology, and comparison vs steroidal AIs. Research use only.
Research Applications
Reversible Aromatase Inhibition
CYP19A1 competitive inhibition Ki, IC50, selectivity over other CYP enzymes
Estradiol Suppression Kinetics
Serum E2 reduction, dose-response, washout and recovery dynamics
Non-Steroidal vs Steroidal AI
Anastrozole vs exemestane — reversible vs irreversible, structural class differences
HPG Axis Estrogen Research
Aromatase inhibition impact on hypothalamic/pituitary ER feedback, LH/FSH
Breast Cancer Models
ER+ tumour estrogen deprivation, AI resistance mechanisms, combination studies
Quick Specs
| Form |
C₁₇H₁₉N₅, MW 293.4 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
120511-73-1 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
QSC raw powder compounds are supplied as bulk crystalline or amorphous powder in a sealed, labelled container at the stated quantity. No reconstitution is required — the powder is ready for weighing and use in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct light. Keep in the original sealed container. Properly stored raw powder remains stable for 2–3 years.
What purity is this QSC compound and how is it verified?
All QSC raw powder compounds are tested to ≥99% purity by HPLC on every production batch, with MS-confirmed identity. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
