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What is Hydroxychloroquine (HCQ)?

Hydroxychloroquine (HCQ) accumulates in lysosomes, raising intra-lysosomal pH and inhibiting lysosomal enzyme activity. Acts as an autophagy flux inhibitor, TLR7/9 antagonist, and immune modulator. Bulk powder for large-scale autophagy inhibition research, innate immune studies, and lysosomal biology. Research use only.

Research Applications

Autophagy Inhibition

LC3-II accumulation, p62 buildup, autolysosome blockade at large scale

TLR7/9 Signalling

Endosomal TLR blockade, IFN-α suppression, innate immune pathway

Lysosomal Biology

pH alkalisation, cathepsin activity, LAMP1/2, lysosomal membrane integrity

Autoimmune Research

Antigen presentation inhibition, MHC-II pathway, macrophage polarisation

Cancer Combination

Autophagy inhibitor in chemotherapy sensitisation — large-scale in vitro studies

 

Quick Specs

Form C₁₈H₂₆ClN₃O, MW 335.9
Purity ≥99% by HPLC — every batch
CAS Number 118-42-3
Molecular Weight MS molecular weight confirmed — every batch
Specification ≥99% by HPLC — every batch
Shelf Life 24 months (unopened)
Storage Room temperature sealed | cool, dry storage
Manufacture In-house synthesis — Qingdao, China
Brand China

Frequently Asked Questions

How do I reconstitute this peptide?
QSC raw powder compounds are supplied as bulk crystalline or amorphous powder in a sealed, labelled container at the stated quantity. No reconstitution is required — the powder is ready for weighing and use in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct light. Keep in the original sealed container. Properly stored raw powder remains stable for 2–3 years.
What purity is this QSC compound and how is it verified?
All QSC raw powder compounds are tested to ≥99% purity by HPLC on every production batch, with MS-confirmed identity. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
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