What is AICAR?
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) is an AMP mimetic that activates AMPK — the master energy sensor. Phosphorylated intracellularly to ZMP, mimicking elevated AMP:ATP ratio. Activates fatty acid oxidation, glucose uptake, mitochondrial biogenesis, and autophagy. Classic research tool for energy sensing and exercise mimetic pharmacology. Research use only.
Research Applications
AMPK Activation
pAMPK, pACC, downstream energy sensing cascade — dose-response
Exercise Mimetic Research
Endurance gene programs — running capacity, fibre type shift, PGC-1α
Glucose Metabolism
GLUT4 translocation, insulin-independent glucose uptake, hepatic glycolysis
Fatty Acid Oxidation
CPT1 derepression, β-oxidation flux, ketogenesis interaction
Autophagy & mTOR
mTORC1 suppression, ULK1 activation, autophagy flux quantification
Quick Specs
| Form |
C₉H₁₄N₄O₈P, MW 338.2 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
2627-69-2 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
QSC raw powder compounds are supplied as bulk crystalline or amorphous powder in a sealed, labelled container at the stated quantity. No reconstitution is required — the powder is ready for weighing and use in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct light. Keep in the original sealed container. Properly stored raw powder remains stable for 2–3 years.
What purity is this QSC compound and how is it verified?
All QSC raw powder compounds are tested to ≥99% purity by HPLC on every production batch, with MS-confirmed identity. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
