What is Prednisone?
Prednisone is a synthetic glucocorticoid prodrug — converted hepatically to active prednisolone. Binds the glucocorticoid receptor (GR) with high affinity, mediating broad anti-inflammatory and immunosuppressive effects via genomic (GRE transactivation/transrepression) and non-genomic pathways. Research tool for GR pharmacology, inflammatory cascade modelling, HPA axis studies, and immunosuppression research. Research use only.
Research Applications
Glucocorticoid Receptor Pharmacology
GR binding, nuclear translocation, GRE-mediated transactivation/transrepression
Anti-Inflammatory Research
NF-κB suppression, AP-1 inhibition, COX-2/PLA2 downregulation, cytokine profiling
HPA Axis Suppression
Cortisol suppression, ACTH feedback, adrenal insufficiency models
Immunosuppression Models
T-cell, B-cell, macrophage suppression — transplant tolerance research
Glucocorticoid-Induced Osteoporosis
Osteoblast suppression, bone turnover markers, fracture risk modelling
Quick Specs
| Form |
C₂₁H₂₆O₅ |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
53-03-2 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
QSC research tablets are supplied as pre-dosed oral tablets at the stated concentration. No reconstitution is required. Each tablet is compressed at uniform dose for consistent dosing in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight. Keep in the original container. Properly stored tablets remain stable for 2–3 years.
What purity is this QSC compound and how is it verified?
QSC research tablets contain active ingredient at ≥99% HPLC purity before tableting, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
