What is Hydroxychloroquine?
Hydroxychloroquine (HCQ) is an aminoquinoline derivative that accumulates in lysosomes, raising intra-lysosomal pH and inhibiting lysosomal enzyme activity. Acts as an autophagy flux inhibitor (blocking autolysosome degradation), a TLR7/9 antagonist (blocking endosomal TLR signalling), and a general immune modulator. Research tool for autophagy biology, innate immune pathway studies, and lysosomal function research. Research use only.
Research Applications
Autophagy Inhibition
Lysosomal pH elevation, autolysosome blockade, LC3-II accumulation, p62 buildup
TLR7/9 Signalling
Endosomal toll-like receptor inhibition, IFN-α suppression, innate immune pathway
Lysosomal Biology
Lysosomal alkalisation, cathepsin activity, LAMP1/LAMP2, lysosomal membrane integrity
Immune Modulation Research
Antigen presentation, MHC-II pathway, dendritic cell function, autoimmune models
Cancer Autophagy Research
HCQ as autophagy inhibitor in combination studies — chemo-sensitisation models
Quick Specs
| Form |
C₁₈H₂₆ClN₃O |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
118-42-3 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months unopened |
| Storage |
Room temperature sealed | cool, dry, dark storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
QSC research capsules are supplied as pre-dosed oral capsules at the stated concentration. No reconstitution is required. Each capsule contains uniform active ingredient for consistent dosing in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct sunlight. Keep in the original container. Properly stored capsules remain stable for 2–3 years.
What purity is this QSC compound and how is it verified?
QSC research capsules contain active ingredient at ≥99% HPLC purity before encapsulation, with MS-confirmed identity on every batch. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry, dark storage
