What is GHK Basic?
GHK Basic is the free tripeptide Gly-His-Lys without copper chelation — the unbound precursor form of GHK-Cu. Naturally present in human plasma at concentrations that decline with age, GHK activates collagen synthesis, antioxidant gene expression, wound repair signalling, and tissue remodelling pathways. The copper-free form is used where isolated peptide activity independent of copper-mediated redox chemistry is required. Research use only.
Research Applications
Collagen Synthesis Research
Fibroblast collagen I/III expression, TGF-β pathway, ECM deposition — isolated from copper effects
Gene Expression Modulation
GHK activation of >4,000 human genes — antioxidant (SOD, catalase), anti-inflammatory, repair
Wound Healing Studies
Keratinocyte migration, fibroblast proliferation, angiogenesis without copper redox contribution
Copper-Free Control Experiments
Baseline GHK tripeptide activity as experimental control vs GHK-Cu chelated form
Skin Aging Research
Age-related plasma GHK decline models, dermal fibroblast senescence, matrix metalloproteinase regulation
Quick Specs
| Form |
C₁₄H₂₄N₆O₄, MW 340.4 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
49557-75-7 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
-20°C sealed | 2–8°C reconstituted (4 weeks) |
| Manufacture |
In-house Fmoc SPPS — Qingdao, China |
| Brand |
Anti-Aging & Longevity |
Frequently Asked Questions
How do I reconstitute this peptide?
Add 1–2 mL bacteriostatic water to the lyophilized vial and swirl gently. GHK Basic is highly water-soluble and dissolves within 30 seconds. Solution appears clear and colourless (no blue colour, as this is the copper-free form).
How should this peptide be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 4 weeks. Without copper chelation, the peptide is more susceptible to oxidation — store protected from light and oxygen.
What purity is this QSC compound and how is it verified?
GHK Basic is the free tripeptide (Gly-His-Lys) without copper. GHK-Cu is the same peptide with a coordinated Cu²⁺ ion, which adds distinct copper-mediated enzymatic and redox activities. GHK Basic allows researchers to isolate the pure peptide effects from copper chemistry.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
-20°C sealed | 2–8°C reconstituted (4 weeks)
