What is Tamoxifen (Nolvadex)?
Tamoxifen is a non-steroidal SERM — acts as an ER antagonist in breast tissue (blocking estradiol-driven proliferation) and as a partial ER agonist in bone and uterine tissue. Active metabolite 4-hydroxytamoxifen has ~100× higher ER affinity. Research tool for ER pharmacology, breast cancer models, and HPG axis reactivation research. Research use only.
Research Applications
ER Antagonism Research
Competitive ER blockade, breast epithelial ER-mediated gene suppression
SERM Tissue Selectivity
Antagonist in breast vs agonist in bone/uterus — tissue-selective ER pharmacology
HPG Axis Reactivation
Hypothalamic ER blockade — LH/FSH upregulation, testosterone restoration models
Breast Cancer Research
ER+ cancer cell proliferation inhibition, resistance mechanism studies
4-OH-Tamoxifen Metabolism
CYP2D6-mediated active metabolite formation, pharmacogenomics
Quick Specs
| Form |
C₂₆H₂₉NO, MW 371.5 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
10540-29-1 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
QSC raw powder compounds are supplied as bulk crystalline or amorphous powder in a sealed, labelled container at the stated quantity. No reconstitution is required — the powder is ready for weighing and use in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct light. Keep in the original sealed container. Properly stored raw powder remains stable for 2–3 years.
What purity is this QSC compound and how is it verified?
All QSC raw powder compounds are tested to ≥99% purity by HPLC on every production batch, with MS-confirmed identity. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
