What is Exemestane (Aromasin)?
Exemestane (Aromasin) is a steroidal suicide aromatase inhibitor — irreversibly inactivates aromatase (CYP19A1) via covalent binding. Structurally similar to androstenedione. Research tool for aromatase enzymology, irreversible enzyme inactivation kinetics, estrogen suppression, and steroidal vs non-steroidal AI comparison. Research use only.
Research Applications
Irreversible Aromatase Inactivation
Suicide substrate kinetics, kcat/kinact determination, CYP19A1 covalent inhibition
Steroidal vs Non-Steroidal AI
Exemestane vs anastrozole/letrozole — mechanism, selectivity, recovery studies
Estrogen Suppression
Estradiol reduction kinetics, tissue estrogen levels, receptor occupancy
Bone Health Research
Estrogen-dependent bone turnover — aromatase inhibition effects on BMD
Post-Aromatase Recovery
New aromatase synthesis after irreversible inactivation — enzyme recovery timeline
Quick Specs
| Form |
C₂₀H₂₄O₂, MW 296.4 |
| Purity |
≥99% by HPLC — every batch |
| CAS Number |
107868-30-4 |
| Molecular Weight |
MS molecular weight confirmed — every batch |
| Specification |
≥99% by HPLC — every batch |
| Shelf Life |
24 months (unopened) |
| Storage |
Room temperature sealed | cool, dry storage |
| Manufacture |
In-house synthesis — Qingdao, China |
| Brand |
China |
Frequently Asked Questions
How do I reconstitute this peptide?
QSC raw powder compounds are supplied as bulk crystalline or amorphous powder in a sealed, labelled container at the stated quantity. No reconstitution is required — the powder is ready for weighing and use in research applications.
How should this peptide be stored?
Store at room temperature (15–25°C) in a cool, dry place away from moisture, heat, and direct light. Keep in the original sealed container. Properly stored raw powder remains stable for 2–3 years.
What purity is this QSC compound and how is it verified?
All QSC raw powder compounds are tested to ≥99% purity by HPLC on every production batch, with MS-confirmed identity. COA is published on the product page and independently verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC's free
peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA 5–7 days
🌏 International shipping: 7–14 days
⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION
QSC products are strictly for in vitro and in vivo laboratory research.
Safety & Handling
🚫
Not for Human Use
These compounds are for research only.
🥽
PPE Required
Always use appropriate protective equipment.
❄️
Storage Compliance
Follow product-specific storage conditions.
Product-Specific Storage
Room temperature sealed | cool, dry storage
